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Niclosamide

Synonyms * 2', 5-Dichlor-4'-nitro-salizylsaeureanilid, * 2', 5-Dichloro-4'-nitrosalicylanilide,
* 2',5-Dichlor-4'-nitro-salizylsaeureanilid,* 2',5-Dichlor-4'-nitro-salizylsaeureanilid [German],
* 2',5-Dichloro-4'-nitrosalicyanilide, * 2-Chloro-4-nitrophenylamide-6-chlorosalicylic acid,
* 2-Hydroxy-5-chloro-N-(2-chloro-4-nitrophenyl)benzamide,
* 5-Chloro-2'-chloro-4'-nitrosalicylanilide,
* 5-Chloro-N-(2'-chloro-4'-nitrophenyl)salicylamide,
* 5-Chloro-N-(2-chloro-4-nitro-phenyl)-2-hydroxy-benzamide,
* 5-Chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide,
* 5-Chlorosalicyloyl-(o-chloro-p-nitranilide),
* AI3-25823, * AIDS-092503, * AIDS092503, * Atenase,
* BAY 2353, * Bayer 2353, * Bayer 73, * Bayluscid,
* Benzamide, 5-chloro-N- (2-chloro-4-nitrophenyl)-2-hydroxy-,
* Benzamide, 5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxy-,
* BRN 2820605, * C07265, * CCRIS 3437, * Cestocid,
* Cestocide, * Chemagro 2353, * CHEMBANK1313,
* CHEMBANK4413, * Clonitralid, * Devermin, * Devermine,
* Dichlosale, * EINECS 200-056-8, * ENT 25823,
* Fedal-Telmin, * Fenasal, * Helmiantin, * HL 2447,
* HSDB 1572, * Iomesan, * Iomezan, * Lintex,
* Mansonil, * Mato, * N-(2'-Chlor-4'-nitrophenyl)-5-chlorsalicylamid,
* N-(2'-Chlor-4'-nitrophenyl)-5-chlorsalicylamid [German],
* N-(2'-Chloro-4'-nitrophenyl)-5-chlorosalicylamide,
* N-(2-Chloro-4-nitrophenyl)-5-chlorosalicylamide,
* N3510, * Nasemo, * Niclocide, * Niclocide (TN),
* Niclosamida [INN-Spanish], * Niclosamide, * Niclosamide [BSI:ISO],
* Niclosamide [USAN:BAN:INN], * Niclosamidum [INN-Latin],
* nicolsamide, * Nitrophenyl chlorsalicylamide, * Sagimid,
* NSC 178296, * NSC178296, * Phenasal, * Radeverm, * Ruby,
* Salicylanilide, 2',5-dichloro-4'-nitro-, * SR 73, * Sulqui, * Telidal,
* Tredemine, * Vermitid, * Vermitin, * WR 46234, * Yomensan, * Yomesan, * Zestocarp
Chemical Name 2',5-dichloro-4'-nitrosalicylanilide
Molecular formula C13H8Cl2N2O44
Molecular weight 327.119
CAS No. 50-65-7
Structural formula
Specification EP/CP(V)
Pharmacodynamic Properties Niclosamide is a lampricide and molluscicide. It kills a wide variety of snails, cestodes(Taenia saginata and Taeniasolium) and Cercariae by affecting the respiration and the carbohydrate metabolism. It probably disturbs oxidation processes by inhibiting oxygen uptake. The main target pest in agricultural use is the golden apple snail (Pomacea canaliculata) in paddy fields (rice-cultivation). It is also used in public health for control of snails which are the intermediate hosts of Schistosoma spp., the infectious agents of schistosomiasis. The compound is quickly metabolized in water and does not exhibit a long-term effect (Andrews et al, 1983). It is also applied to commercially managed fish ponds, in order to clean them from undesirable fish prior to re-filling the pond. Niclosamide is highly toxic to fish but, due to its short half-life in water, the batch of new fish may be added only a few days after application of the pesticide.
Storage Keep container tightly closed in a cool, well-ventilated area.
MSDS Provide as per request after the order or contract is signed.

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